Organocatalytic dynamic kinetic resolution via conjugate addition: synthesis of chiral trans-2,5-dialkylcyclohexanones.

نویسندگان

  • Ganesh Pandey
  • Priyanka A Adate
  • Vedavati G Puranik
چکیده

A novel strategy of initiating an organocatalysed dynamic kinetic resolution (dr up to 99 : 1 and er up to 94 : 6) for the synthesis of chiral trans-2,5-dialkylcyclohexanones by an asymmetric conjugate addition of dimethyl malonate on to 6-substituted cyclohexenones is reported.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 10 41  شماره 

صفحات  -

تاریخ انتشار 2012